This is my personal blog, which is about news in general. we have a collaboration, with Mashable. my blog It's called ''Find a way out of reality'' why?, I ask you that question. find a way to escape reality.
to foreign enemies which already have it 🤷♂️ think they were breached recently big time hence most of the why to this 🤷♂️ I could be wrong but I got a letter from them stating some information was leaked
James M. Benavides What? They haven’t been able to exploit the secrets of people’s genetics for profit? 11 h Responder Laura Puga Mashable 🎺 PRIMER JUICIO DE LAS TROMPETAS DE DIOS: LLOVERÁ GRANIZO Y FUEGO 🔥 MEZCLADOS CON SANGRE 🩸 ❗ 🙏 GRACIAS A MI CRISTO QUE NOS PERMITE RESPIRAR ❤️ 📖 La Biblia dice: EL PRIMER ÁNGEL TOCÓ LA TROMPETA, Y HUBO GRANIZO Y FUEGO 🔥 MEZCLADOS CON SANGRE 🩸 QUE FUERON LANZADOS SOBRE LA TIERRA 🌎 Y la tercera parte de los árboles se quemó, y SE QUEMÓ TODA LA HIERBA VERDE Ap 8:7. 👉 Quiero recordarles que ESTE SEGUNDO BLOQUE DE LOS 7 JUICIOS ( castigos) DE LAS TROMPETAS DE DIOS, serán en esta tierra DESPUÉS DEL PRÓXIMO ARREBATAMIENTO 👆 DE LA IGLESIA CRISTIANA AL CIELO 1 Ts 4:16-17 Y DESPUÉS DEL PRIMER BLOQUE DE LOS 7 JUICIOS DE LOS SELLOS DE DIOS. 🚨 LOS BLOQUES DE JUICIOS IRÁN EN AUMENTO A CAUSA DE LA IRA 😡 DE DIOS que la misma humanidad está provocando a Cristo EL DUEÑO Y SEÑOR DE TODA ESTA TIERRA Salmo 24:1-2❗Esto se los advierto a los que se creen dueños de la tierra. 👉 COMO SERÁ ESTE JUICIO DE LA PRIMER TROMPETA ❓ Cristo en el cielo LE VA A ORDENAR A UN ÁNGEL QUE ABRA LAS COMPUERTAS DE LOS ALMACENES DE GRANIZO QUE EL TIENE 👆 EN EL CIELO Y lo lance 😡👇 a los rebeldes de la tierra 😏 📖 La Biblia dice: Has entrado tú en los tesoros de la nieve, o HAS VISTO LOS TESOROS DEL GRANIZO, que tengo reservados para el tiempo de angustia, PARA EL DÍA DE LA GUERRA Y DE LA BATALLA❓Job 38:22-23. ⚠️ CAERÁN DESDE LOS CIELOS BOLAS DE GRANIZO, CON FUEGO 🔥 Y CON SANGRE 🩸 de color rojo. CRISTO ESTARÁ VENGANDO SU SACRIFICIO EN LA CRUZ por eso caerá sangre a la tierra. 🛑 LOS IGNORANTES QUE NO SON CRISTIANOS Y QUE NO ENTIENDEN LA BIBLIA ( falsos 🐕🦺 apóstoles de la prosperidad y 🤥 falsos testigos de Jehová) DICEN: ESTOS JUICIOS YA SUCEDIERON EN LAS PLAGAS DEL TIEMPO DE MOISES❗ Les voy a demostrar con la Biblia QUE LA ESTÁN CALUMNIANDO: 👉 EN EL TIEMPO DE MOISÉS HUBO UNA PLAGA DE GRANIZO: 📖 La Biblia dice: Hubo, pues, GRANIZO, Y FUEGO 🔥 MEZCLADO CON GRANIZO, tan grande, cuál nunca hubo en toda la tierra de Egipto desde que fue habitada Ex 9:24. En esta plaga o castigo que Dios envío al pueblo de Israel 🇮🇱 por rebeldes, CAYERON BOLAS DE GRANIZO CON FUEGO 🔥 PERO SIN SANGRE Y en este juicio de la primer trompeta LAS BOLAS DE GRANIZO SERÁN CON FUEGO Y CON SANGRE 🩸 Por eso SON JUICIOS PARECIDOS PERO DIFERENTES❗ ⚠️ Las personas que NO QUIERAN VIVIR ESTOS CASTIGOS DE DIOS DEBEN: 🧎 ARREPENTIRSE de sus maldades y CREER ÚNICAMENTE EN CRISTO Mr 1:15 Y ESTAR 👂 OYENDO TODOS LOS DIAS LA SANA DOCTRINA DE JESÚS Tito 2:1 es el único evangelio verdadero y así OYENDO LA PALABRA DE DIOS TENDRÁS TU FE FUNDAMENTADA EN LA BIBLIA 1 Co 3:11. 👉 Escucha en YOUTUBE: CHUY OLIVARES Y DAVID DIAMOND ( próximas profecías bíblicas) RECORDEMOS QUE EN CUALQUIER INSTANTE LA IGLESIA CRISTIANA SEREMOS ARREBATADA AL CIELO ☝️ para escapar del próximo gobierno mundial del anticristo Ap 13:7 y de los 21 juicios de Dios. Les amo en Cristo ❤️📖💪🙏☝️
I still can't believe people willingly handed over their DNA to some random company. Now where does that information land? Will Elon buy the company and then have access to all that data?
I handed over my DNA out of sheer desperation to find my birth mother after searching continents for 30 plus yrs , happy to report 23 and Me was able to reunite me with my biological family.
I have no clue, but finding my birth family was my only dream growing up so feeling super fulfilled and hoping my DNA doesn't end up at any crime scene 😂
FT: have you fact-checked that DIP loan? According to Pitchbook.com: "JMB Capital Partners is a private equity based in Los Angeles, California. The firm was terminated on 11th December 2018."
The only thing to be commended here is the board (two of them) installed by the incompetent CEO who each refused to sell the company to her. She is not fit to run this company or safeguard the data.
As a geneticist and someone who met Anne Wojcicki a few times, I was not impressed. She was smug and arrogant, far more than someone with very little training in the field should be. I told her their standard DNA analysis tech was obsolete, which it was circa 2010. (I was trying to get her interested in a tech startup based on NGS that I had founded.) The genetic models they applied to complex disease were never proven or reliable (and still aren't), resulting in the FDA beatdown. I never really saw evidence of a good or concrete business model, but that is outside my core expertise.
By the way, 23andme (and still-extant competitor Ancestry) do not perform DNA sequencing, at least not on the vast majority of samples they receive (and what you pay 100 USD +/- for). They used a low density SNP array for genealogy. The only truly useful information they ever could have had would have been whole genome sequence combined with detailed (i.e. quantitative) medical histories. Obtaining that would have been vastly more expensive and difficult, particularly the latter.
If they still have all those DNA samples banked and suitable for for high coverage whole genome sequencing--quite unlikely given the method of sample collection via saliva kit--that would be worth a great deal, particularly if combined with demographic and at least some health data.
Concerns about genetic privacy are in general quite overblown, unless you or your relatives are leaving DNA samples at crime sites.
She had an actual product, but did nothing with it other than oversell its very limited potential. I doubt there is anything that rises to the level of fraud, though.
Grifter . A company founded on finding relatives that actually wanted to be a biotech firm . Kind of like a company that wants to connect people turning out to be the world’s biggest advertising firm .
One can see that the database could be a tad useful to health insurers and annuity companies. However, past customers might feel a little more neanderthal for having relinquished their bio blueprint.
The only benefits I saw in the app, beyond the initial assessment was to be able to find potential relatives based on DNA matches, the reality is that they are obviously really few matches, beyond your immediate relatives which is obvious and don't provide much values unless of course you don't match with your siblings, then it's probably an interesting conversation.
Such poor reporting. A critical point in the history of 23andme is that it was set up to mine genomics data at scale to provide subscribers with medical information, inclusive of disease prediction until the FDA shut it down. It then had no alternative to switch to ancestry, but had negotiated ~2 diseases it could include in its portfolio with the FDA. Clearly, it was too much to expect a disease-by-disease negotiation to work!
Perhaps you could be kind and say it was ahead of its time, but I think it is much more a story of having the wrong people driving it, without the knowledge, skills and clear vision to get beyond the chasm of despair.
Now, of course, we're even further in our advances and technology - you can have stem cell therapy in a Japanese clinic for ~$5k (albeit a lot of potential issues there) for various injuries and diseases. Maybe brighter people can utilise their DB and it would be better perhaps if it became an academic resource, similar to the work of George Church, et al.
Also, important to remember that DNA profiling is one aspect of a complex personal story for each of us.
PS I instructed them to purge all my data after their first publicly declaired data breach. The company was a mess and will be in a sorry state for any potential buyer, should go for a song, which may undervalue at least the DB
The Wojcicki family. Where "success" is defined as maximizing cash. The sister, Susan Wojcicki, now deceased, ran YouTube and FLOODED it with fraudulent "U.S. Government Giveaway for Seniors" ads, which only put debt ridden seniors deeper into debt. No rules, no ethics. Just "success." Anne illegally sold customers data to whomever would buy it. No tears for either of them. A scam is a scam is a scam.
People, the point of getting your genome sequenced is *not* so that you can bore strangers by droning on that you are 1/32 part Hungarian and 43% cro magnon: genetic testing, especially at birth, can save lives by identifying for example a likely vulnerability to some dietary factor, or a predisposition to develop some disease if exposed to a given poison or stress. This can be hard knowledge to have, if there is nothing to be done, but also incredibly valuable in the (many) cases where there are actions that can be taken. Evolution has actually done pretty good work on us: many genetic conditions are not problems but adaptations when matched to the right diet or lifestyle.
From a valuation of $5.3n to $50million simply does not make sense……how credible are these valuations ? Or has it been deliberately undervalued so she can buy it for a song ? This is not mathing…..
Probably a 30 under 30 star at some point. Profitability (positive) should be a requirement for any accolades, prizes, etc rqther than being good at selling equity
A near 20 year history and almost five years as a listed company, yet it has never generated a profit. Few things encapsulate American exceptionalism to the extent of optional profitability.
wait I thought I owned by DNA, because.. dunno - my bad - guess we have to now enforce diversity, equity and inclusion when it comes to sharing DNA across the globe, hmm
I'm sure all those that rushed to give them their DNA to be told they are 5% whatever will be delighted that the company will be sold for pennies to someone...
Classic early-adopter syndrome, the next genomics company will be a big success. Or perhaps it won't be a company: this valuable function of collecting and managing human genetic data sits naturally within a (functional, halfway-sane) government, and is managed well in Sweden as a national platform:
Data management and informatics | Genomic Medicine Sweden https://genomicmedicine.se/en/data-management-informatics/
I think ancestry is better but I have no skin (or genes) in the game to make me take the side of either company as they both have my DNA (ancestry just has a much wider range of services - it is owned by Blackstone)
I am a customer of Ancestry and I think their business model is much better than 23andme. With Ancestry you have an incentive to subscribe because you can always do more work on your tree, and you are occasionally receiving DnA matches from other users. I find it fascinating. I use it also as a shared family photo album. I hope that it will reduce the guilt I feel when I eventually throw away most of my parents’ and grandparents’ thousands of holiday snaps.
This failure illustrates yet again why giving founders special share rights in public companies cuts both ways. The company could not do anything the founder chose not to do, even as it failed.
What are the legal constraints on trading a DNA database, if any?
I feel vindicated for ignoring all the 23 and Me packs I got gifted. Never felt comfortable with the idea of any private company owning my genetic information.
They don’t “own your genetic information”. That is, literally, illegal. All their business model meant is that they had a copy of some of your genetic information. Which, by itself, is literally without value. What’s valuable is having access to the aggregated data of millions of people, and in that context your individual information is pretty meaningless.
Are you purposely misunderstanding the point?23andMe “owns” a person genetic data in the sense they presumably have the rights to sell a copy to whomever they want. This includes insurance companies seeking to base premiums on genetic factors.
It is not clear that legally they could sell an individual’s information without their consent: that depends on the customer and the proposed use.
What they can sell is the aggregate data, which is anonymized. So, no, it’s really not accurate to say “23andMe “owns” a person genetic data in the sense they presumably have the rights to sell a copy to whomever they want.”
People who don’t work with data are generally pretty poor at understanding the legal difference between an individual’s personal information and the data derived from it, and what ownership means.
I’m not trying to be argumentative, just trying to damp down the “OMG, they can do whatever they want with my information“ vibe coming off some of the posts.
In addition, the level of genomic data they have for probably 95% (or more) of the DNAs they banked is simply low-resolution haplotypes. Typically that analysis is of something on the order of 6000 polymorphisms spread across 3 billion base pairs of human DNA. Sufficient for genealogy, but not for finding genetic disease associations with any degree of precision.
Title 1 of the Genetic Information Nondiscrimination Act (GINA) [Public Law 110-233] makes it explicitly illegal for health insurers or employers to use a person's genetic information to determine eligibility or premiums, or to request that they undergo genetic tests. Even storing such data can be problematic for insurers under the Health Insurance Portability and Accountability Act (HIPAA) of 1996.
We know that business in the US blatantly ignores law, and not just anti trust law. Could given you dozens of past and recent examples in well known US brand names here
I imagine the FBI or other law enforcement agencies will have a keen interest to get their data on this wide database.
A bit concerning that folks rarely have the concern about law enforcement readily accessing information that would have otherwise been subject to a warrant.
Benefiting from cheap and easy genetic sequencing is easy science (today) but very challenging for healthcare professionals who graduated university 25+ years ago when the technology didn't exist, and an absolute screaming nightmare for governments, which are run by people with no comprehension of science whatsoever and a very limited grasp of ethics it would sometimes seem.
Well, the business has an inherent problem, in that you only need to do one spit in your life, and if you are happy with family resemblences, only one in a family needs to do it, and outside the Americas, most of us have a pretty good idea of our heritage from family records.
Genetic diseases are better tested for on an individual basis anyway, and again, most of us know what our grandparents and cousins died of - no-one has died of cancer in my family as far back as we can go, cardio-vascular is the killer on both sides.
"good idea of our heritage from family records." We may think so, but one problem when genetic testing began many years ago, was the rather large proportion of test subjects, who turned out to have another father, than they thought. ( I had a colleage from the Faroes, with your name, a very nice lady, many years ago, btw).
To be fair, I did say family resemblances, and when I said heritage, I meant in terms of geography. No 2% sub-saharan African or Sephardic Jewish turned up when my brother did ours, nor did we expect it to, since dad did our family tree back to the 1700s. Censuses and parish records showed how little we moved around the world.
And while I may have a distant link to your colleague, (because, you know, vikings), being called Jonsdottir just means you are female, and your dad was called Jon. I highly recommend a trip to the Faroes - stunning place, but maybe not if you are a vegetarian.
I know the patronym idea and do not really believe you are related. but I guessed you would hail from the Faroes, so you know how relatively isolated communities work.
Not sure skerpikjøt is for me..... The viking trade routes, went very far...
In Mikael Niemi's "Popular music from Vittula" ( I think) one part of coming of age for the protagonist, was when his father, in the sauna, informed him about the biological sister or two, he had in the village, unknown to his mother. The implicit message: leave them alone ("One was rather cute" he noted with some misgivings).
Yeah, that's the Finns though. Easy to leave children behind you when you've got the whole of the Scandi peninsula and the Baltics to follow the reindeer round!!
Though... is that why parish records became a thing generally? To keep track of who in the village you can safely have kids with?
It was both. Inheritance (and taxation!) were important factors, particularly because in much of pre-modern Europe, inheritance was not strictly patrilineal.
In Denmark, for example, before Frederick V, land had be to divided equally among the children with women getting a half share, but after the land reforms, the big estates called Len (in English entailed estates) had to pass down the male line intact, which meant that it was important not just to know who your children were but also potential heirs among your cousins.
Incidentally, England had similar laws: this is what drives the plot in Jane Austen's Pride and Prejudice, for example. Mr. Bennett is relatively wealthy, but his daughters and wife are faced with poverty if he dies, because all his wealth is tied up in his property and by law that has to go to his closest male relative. In this case, since he has no sons, it's a relatively unknown male cousin.
But it was also important to prevent what were called "consanguineous marriages": this has been the case in Europe since at least the Roman republic.
Note that the California DoJ Attorney General issued urgent advice for 23andMe customers to delete their data on Friday: https://oag.ca.gov/news/press-releases/attorney-general-bonta-urgently-issues-consumer-alert-23andme-customers
It seems sensible to follow the instructions to avoid your data being caught up as assets for sale.
Wojcicki has run this business into the ground with her blind ambition. Her vignette on Bloomberg was a big, red flag—as many of them are. They should do a ‘where are they now’.
Where will all that DNA go??
ReplyDeleteto foreign enemies which already have it 🤷♂️ think they were breached recently big time hence most of the why to this 🤷♂️ I could be wrong but I got a letter from them stating some information was leaked
DeleteGo woke go broke
ReplyDeleteHow TF is that "woke."
Deletebe lame with no brain
DeleteThanks for the suggestion for my word filter.
DeleteWild concept that commodifying the human genome didn't pan out
ReplyDeleteI bet he sold all your data for a pretty penny before he bounced.
ReplyDeletesure cus a CEO ofc can't be a woman🙄
DeleteWhat? They haven’t been able to exploit the secrets of people’s genetics for profit?
ReplyDelete
ReplyDeleteJames M. Benavides
What? They haven’t been able to exploit the secrets of people’s genetics for profit?
11 h
Responder
Laura Puga
Mashable
🎺 PRIMER JUICIO DE LAS TROMPETAS DE DIOS: LLOVERÁ GRANIZO Y FUEGO 🔥 MEZCLADOS CON SANGRE 🩸 ❗
🙏 GRACIAS A MI CRISTO QUE NOS PERMITE RESPIRAR ❤️
📖 La Biblia dice: EL PRIMER ÁNGEL TOCÓ LA TROMPETA, Y HUBO GRANIZO Y FUEGO 🔥 MEZCLADOS CON SANGRE 🩸 QUE FUERON LANZADOS SOBRE LA TIERRA 🌎 Y la tercera parte de los árboles se quemó, y SE QUEMÓ TODA LA HIERBA VERDE Ap 8:7.
👉 Quiero recordarles que ESTE SEGUNDO BLOQUE DE LOS 7 JUICIOS ( castigos) DE LAS TROMPETAS DE DIOS, serán en esta tierra DESPUÉS DEL PRÓXIMO ARREBATAMIENTO 👆 DE LA IGLESIA CRISTIANA AL CIELO 1 Ts 4:16-17 Y DESPUÉS DEL PRIMER BLOQUE DE LOS 7 JUICIOS DE LOS SELLOS DE DIOS.
🚨 LOS BLOQUES DE JUICIOS IRÁN EN AUMENTO A CAUSA DE LA IRA 😡 DE DIOS que la misma humanidad está provocando a Cristo EL DUEÑO Y SEÑOR DE TODA ESTA TIERRA Salmo 24:1-2❗Esto se los advierto a los que se creen dueños de la tierra.
👉 COMO SERÁ ESTE JUICIO DE LA PRIMER TROMPETA ❓
Cristo en el cielo LE VA A ORDENAR A UN ÁNGEL QUE ABRA LAS COMPUERTAS DE LOS ALMACENES DE GRANIZO QUE EL TIENE 👆 EN EL CIELO Y lo lance 😡👇 a los rebeldes de la tierra 😏
📖 La Biblia dice: Has entrado tú en los tesoros de la nieve, o HAS VISTO LOS TESOROS DEL GRANIZO, que tengo reservados para el tiempo de angustia, PARA EL DÍA DE LA GUERRA Y DE LA BATALLA❓Job 38:22-23.
⚠️ CAERÁN DESDE LOS CIELOS BOLAS DE GRANIZO, CON FUEGO 🔥 Y CON SANGRE 🩸 de color rojo.
CRISTO ESTARÁ VENGANDO SU SACRIFICIO EN LA CRUZ por eso caerá sangre a la tierra.
🛑 LOS IGNORANTES QUE NO SON CRISTIANOS Y QUE NO ENTIENDEN LA BIBLIA ( falsos 🐕🦺 apóstoles de la prosperidad y 🤥 falsos testigos de Jehová) DICEN:
ESTOS JUICIOS YA SUCEDIERON EN LAS PLAGAS DEL TIEMPO DE MOISES❗
Les voy a demostrar con la Biblia QUE LA ESTÁN CALUMNIANDO:
👉 EN EL TIEMPO DE MOISÉS HUBO UNA PLAGA DE GRANIZO:
📖 La Biblia dice: Hubo, pues, GRANIZO, Y FUEGO 🔥 MEZCLADO CON GRANIZO, tan grande, cuál nunca hubo en toda la tierra de Egipto desde que fue habitada Ex 9:24.
En esta plaga o castigo que Dios envío al pueblo de Israel 🇮🇱 por rebeldes, CAYERON BOLAS DE GRANIZO CON FUEGO 🔥 PERO SIN SANGRE Y en este juicio de la primer trompeta LAS BOLAS DE GRANIZO SERÁN CON FUEGO Y CON SANGRE 🩸 Por eso SON JUICIOS PARECIDOS PERO DIFERENTES❗
⚠️ Las personas que NO QUIERAN VIVIR ESTOS CASTIGOS DE DIOS DEBEN:
🧎 ARREPENTIRSE de sus maldades y CREER ÚNICAMENTE EN CRISTO Mr 1:15 Y ESTAR 👂 OYENDO TODOS LOS DIAS LA SANA DOCTRINA DE JESÚS Tito 2:1 es el único evangelio verdadero y así OYENDO LA PALABRA DE DIOS TENDRÁS TU FE FUNDAMENTADA EN LA BIBLIA 1 Co 3:11.
👉 Escucha en YOUTUBE: CHUY OLIVARES Y DAVID DIAMOND ( próximas profecías bíblicas)
RECORDEMOS QUE EN CUALQUIER INSTANTE LA IGLESIA CRISTIANA SEREMOS ARREBATADA AL CIELO ☝️ para escapar del próximo gobierno mundial del anticristo Ap 13:7 y de los 21 juicios de Dios.
Les amo en Cristo ❤️📖💪🙏☝️
I'm not surprised.
ReplyDeleteThat info cost more than 6000M USD
ReplyDeleteI still can't believe people willingly handed over their DNA to some random company. Now where does that information land? Will Elon buy the company and then have access to all that data?
ReplyDeleteprobably
DeleteI handed over my DNA out of sheer desperation to find my birth mother after searching continents for 30 plus yrs , happy to report 23 and Me was able to reunite me with my biological family.
DeleteFabulous. What happens with your DNA now.?
DeleteI have no clue, but finding my birth family was my only dream growing up so feeling super fulfilled and hoping my DNA doesn't end up at any crime scene 😂
DeleteThere goes everyone's private data up for sale!
ReplyDeleteFT: have you fact-checked that DIP loan?
ReplyDeleteAccording to Pitchbook.com:
"JMB Capital Partners is a private equity based in Los Angeles, California. The firm was terminated on 11th December 2018."
The only thing to be commended here is the board (two of them) installed by the incompetent CEO who each refused to sell the company to her. She is not fit to run this company or safeguard the data.
ReplyDeleteThe data needs monetizing not protecting
DeleteWhat's going to happen to all the 'confidential' DNA data?
ReplyDeleteScooped up by meta and linked to your insta profile and WhatsApp account…
DeleteSold to the highest bidder—North Korea, perhaps
DeleteDon’t forget to log in and request deletion of your data before it’s too late and gets sold to some broker.
ReplyDeleteAs a geneticist and someone who met Anne Wojcicki a few times, I was not impressed. She was smug and arrogant, far more than someone with very little training in the field should be. I told her their standard DNA analysis tech was obsolete, which it was circa 2010. (I was trying to get her interested in a tech startup based on NGS that I had founded.) The genetic models they applied to complex disease were never proven or reliable (and still aren't), resulting in the FDA beatdown. I never really saw evidence of a good or concrete business model, but that is outside my core expertise.
ReplyDeleteBy the way, 23andme (and still-extant competitor Ancestry) do not perform DNA sequencing, at least not on the vast majority of samples they receive (and what you pay 100 USD +/- for). They used a low density SNP array for genealogy. The only truly useful information they ever could have had would have been whole genome sequence combined with detailed (i.e. quantitative) medical histories. Obtaining that would have been vastly more expensive and difficult, particularly the latter.
If they still have all those DNA samples banked and suitable for for high coverage whole genome sequencing--quite unlikely given the method of sample collection via saliva kit--that would be worth a great deal, particularly if combined with demographic and at least some health data.
Concerns about genetic privacy are in general quite overblown, unless you or your relatives are leaving DNA samples at crime sites.
Does she have the Elizabeth Holmes (of Theranos) syndrome?
DeleteShe had an actual product, but did nothing with it other than oversell its very limited potential. I doubt there is anything that rises to the level of fraud, though.
DeleteUSA- how can a company make no profit and still have a $5.8bn market cap in February 2021?
ReplyDeleteNo profit? I repeat it’s a loss making company.
when is a dead parrot not a dead parrot?
DeleteGrifter . A company founded on finding relatives that actually wanted to be a biotech firm . Kind of like a company that wants to connect people turning out to be the world’s biggest advertising firm .
ReplyDeleteOne can see that the database could be a tad useful to health insurers and annuity companies. However, past customers might feel a little more neanderthal for having relinquished their bio blueprint.
ReplyDeleteThe only benefits I saw in the app, beyond the initial assessment was to be able to find potential relatives based on DNA matches, the reality is that they are obviously really few matches, beyond your immediate relatives which is obvious and don't provide much values unless of course you don't match with your siblings, then it's probably an interesting conversation.
ReplyDeleteSuch poor reporting. A critical point in the history of 23andme is that it was set up to mine genomics data at scale to provide subscribers with medical information, inclusive of disease prediction until the FDA shut it down. It then had no alternative to switch to ancestry, but had negotiated ~2 diseases it could include in its portfolio with the FDA. Clearly, it was too much to expect a disease-by-disease negotiation to work!
ReplyDeletePerhaps you could be kind and say it was ahead of its time, but I think it is much more a story of having the wrong people driving it, without the knowledge, skills and clear vision to get beyond the chasm of despair.
Now, of course, we're even further in our advances and technology - you can have stem cell therapy in a Japanese clinic for ~$5k (albeit a lot of potential issues there) for various injuries and diseases. Maybe brighter people can utilise their DB and it would be better perhaps if it became an academic resource, similar to the work of George Church, et al.
Also, important to remember that DNA profiling is one aspect of a complex personal story for each of us.
PS I instructed them to purge all my data after their first publicly declaired data breach. The company was a mess and will be in a sorry state for any potential buyer, should go for a song, which may undervalue at least the DB
Little kindness in business .
DeleteProof that fake until you make it is a bygone product of America's rotten finance..
ReplyDeleteMore Euro-whinging?
DeleteThe Wojcicki family. Where "success" is defined as maximizing cash.
ReplyDeleteThe sister, Susan Wojcicki, now deceased, ran YouTube and FLOODED it with fraudulent "U.S.
Government Giveaway for Seniors" ads, which only put debt ridden seniors deeper into debt.
No rules, no ethics. Just "success."
Anne illegally sold customers data to whomever would buy it. No tears for either of them. A scam is a scam is a scam.
It’s maximising cash at all costs de rigueur nowadays in the US?
DeletePeople, the point of getting your genome sequenced is *not* so that you can bore strangers by droning on that you are 1/32 part Hungarian and 43% cro magnon: genetic testing, especially at birth, can save lives by identifying for example a likely vulnerability to some dietary factor, or a predisposition to develop some disease if exposed to a given poison or stress. This can be hard knowledge to have, if there is nothing to be done, but also incredibly valuable in the (many) cases where there are actions that can be taken. Evolution has actually done pretty good work on us: many genetic conditions are not problems but adaptations when matched to the right diet or lifestyle.
ReplyDeleteAll that DNA data being sold to the highest (?) bidder!
ReplyDelete23 and me has sold that data to others over time.
DeleteYes, the data was always up for sale, but I had to make a pithy comment!
DeletePerhaps they can combine with DOGE and rationalise and optimise the US populace at source?
ReplyDeleteTheir database is a eugenicist's wet dream.
DeleteIt's amazing because you don't even have to have everyone in it. You can triangulate people based on their relatives' DNA sequences.
From a valuation of $5.3n to $50million simply does not make sense……how credible are these valuations ? Or has it been deliberately undervalued so she can buy it for a song ? This is not mathing…..
ReplyDeleteAre you coming to start up valuations late? Especially the wild world of US ratings and valuations.
DeleteProbably a 30 under 30 star at some point. Profitability (positive) should be a requirement for any accolades, prizes, etc rqther than being good at selling equity
ReplyDeleteI will buy the company if they can prove that Donald Trump is in fact a mix of a clown, a Monkey, a ferret and an overachieving ideology.
ReplyDeleteAlas, there is no ferret. It's only rat.
DeleteSounds like too much human dna🤔
DeleteA near 20 year history and almost five years as a listed company, yet it has never generated a profit.
ReplyDeleteFew things encapsulate American exceptionalism to the extent of optional profitability.
wait I thought I owned by DNA, because.. dunno - my bad - guess we have to now enforce diversity, equity and inclusion when it comes to sharing DNA across the globe, hmm
ReplyDelete....when women win...lean in...
ReplyDeleteI'm sure all those that rushed to give them their DNA to be told they are 5% whatever will be delighted that the company will be sold for pennies to someone...
ReplyDeleteInteresting, it seems skill vs gender drives the effectivness of a CEO.
ReplyDeleteLike a Ruchir Sharma article - just a catchy title.
ReplyDeleteFoolish company, silly CEO.
ReplyDeleteFoolish investors?
DeleteIndeed
DeleteThe CEO did very, very well out of it indeed. She clearly played her hand well. It's the investors who are left holding the bag.
DeleteClassic early-adopter syndrome, the next genomics company will be a big success. Or perhaps it won't be a company: this valuable function of collecting and managing human genetic data sits naturally within a (functional, halfway-sane) government, and is managed well in Sweden as a national platform:
ReplyDeleteData management and informatics | Genomic Medicine Sweden
https://genomicmedicine.se/en/data-management-informatics/
I think ancestry is better but I have no skin (or genes) in the game to make me take the side of either company as they both have my DNA (ancestry just has a much wider range of services - it is owned by Blackstone)
DeleteI am a customer of Ancestry and I think their business model is much better than 23andme. With Ancestry you have an incentive to subscribe because you can always do more work on your tree, and you are occasionally receiving DnA matches from other users. I find it fascinating. I use it also as a shared family photo album. I hope that it will reduce the guilt I feel when I eventually throw away most of my parents’ and grandparents’ thousands of holiday snaps.
Deleteyes sure. Just don't forget Sweden and eugenics.
ReplyDeleteI donm't trust any government, especially a socialist one, with my DNA.
Well, I mean, I don't like to bring up the Austrian guy, but...
DeleteGregor Mendel? The man that created genetic science… you meant that guy… right?
DeleteDont worry DOGE will rationalise you before any Swedish institute will think of you
DeleteEugenics? That Annie Lennox has a lot to answer for.
DeleteThis failure illustrates yet again why giving founders special share rights in public companies cuts both ways. The company could not do anything the founder chose not to do, even as it failed.
ReplyDeleteWhat are the legal constraints on trading a DNA database, if any?
I wonder who will buy the genetic database and what they will do with it...
ReplyDeleteI feel vindicated for ignoring all the 23 and Me packs I got gifted. Never felt comfortable with the idea of any private company owning my genetic information.
DeleteThey don’t “own your genetic information”. That is, literally, illegal. All their business model meant is that they had a copy of some of your genetic information. Which, by itself, is literally without value.
DeleteWhat’s valuable is having access to the aggregated data of millions of people, and in that context your individual information is pretty meaningless.
Are you purposely misunderstanding the point?23andMe “owns” a person genetic data in the sense they presumably have the rights to sell a copy to whomever they want. This includes insurance companies seeking to base premiums on genetic factors.
DeleteIt is not clear that legally they could sell an individual’s information without their consent: that depends on the customer and the proposed use.
DeleteWhat they can sell is the aggregate data, which is anonymized. So, no, it’s really not accurate to say “23andMe “owns” a person genetic data in the sense they presumably have the rights to sell a copy to whomever they want.”
People who don’t work with data are generally pretty poor at understanding the legal difference between an individual’s personal information and the data derived from it, and what ownership means.
I’m not trying to be argumentative, just trying to damp down the “OMG, they can do whatever they want with my information“ vibe coming off some of the posts.
In addition, the level of genomic data they have for probably 95% (or more) of the DNAs they banked is simply low-resolution haplotypes. Typically that analysis is of something on the order of 6000 polymorphisms spread across 3 billion base pairs of human DNA. Sufficient for genealogy, but not for finding genetic disease associations with any degree of precision.
DeleteYour individual genetic information is certainly far from meaningless at the law enforcement level.
DeleteI hope you at least wore the sweater your mother-in-law bought you, though.
ReplyDeleteOnly when she comes around 😉
DeleteClone you.
ReplyDeleteOr deny medical insurance because you’re genetically prone to a disease.
DeleteTitle 1 of the Genetic Information Nondiscrimination Act (GINA) [Public Law 110-233] makes it explicitly illegal for health insurers or employers to use a person's genetic information to determine eligibility or premiums, or to request that they undergo genetic tests. Even storing such data can be problematic for insurers under the Health Insurance Portability and Accountability Act (HIPAA) of 1996.
DeleteSo no, that's not really an issue.
Yea, like the rule of law means anything in America anymore.
DeletePrecisely what I was thinking… Laws are transient at best.
DeleteWe know that business in the US blatantly ignores law, and not just anti trust law. Could given you dozens of past and recent examples in well known US brand names here
DeleteThe overwhelming majority of businesses follow the law. But obviously naming exceptions (which you didn’t give) proves what?
Deleteillegal, but not impossible.
Deleteand needs mukst.
someday, elon, the federals, or some kind of organisation Will Use this information.
I imagine the FBI or other law enforcement agencies will have a keen interest to get their data on this wide database.
DeleteA bit concerning that folks rarely have the concern about law enforcement readily accessing information that would have otherwise been subject to a warrant.
Genetics is easy but does not really matters. Proteomics matters but is much more complex
ReplyDeleteBenefiting from cheap and easy genetic sequencing is easy science (today) but very challenging for healthcare professionals who graduated university 25+ years ago when the technology didn't exist, and an absolute screaming nightmare for governments, which are run by people with no comprehension of science whatsoever and a very limited grasp of ethics it would sometimes seem.
DeleteWell, the business has an inherent problem, in that you only need to do one spit in your life, and if you are happy with family resemblences, only one in a family needs to do it, and outside the Americas, most of us have a pretty good idea of our heritage from family records.
ReplyDeleteGenetic diseases are better tested for on an individual basis anyway, and again, most of us know what our grandparents and cousins died of - no-one has died of cancer in my family as far back as we can go, cardio-vascular is the killer on both sides.
"good idea of our heritage from family records."
DeleteWe may think so, but one problem when genetic testing began many years ago, was the rather large proportion of test subjects, who turned out to have another father, than they thought.
( I had a colleage from the Faroes, with your name, a very nice lady, many years ago, btw).
To be fair, I did say family resemblances, and when I said heritage, I meant in terms of geography. No 2% sub-saharan African or Sephardic Jewish turned up when my brother did ours, nor did we expect it to, since dad did our family tree back to the 1700s. Censuses and parish records showed how little we moved around the world.
DeleteAnd while I may have a distant link to your colleague, (because, you know, vikings), being called Jonsdottir just means you are female, and your dad was called Jon. I highly recommend a trip to the Faroes - stunning place, but maybe not if you are a vegetarian.
I know the patronym idea and do not really believe you are related. but I guessed you would hail from the Faroes, so you know how relatively isolated communities work.
DeleteNot sure skerpikjøt is for me..... The viking trade routes, went very far...
In Mikael Niemi's "Popular music from Vittula" ( I think) one part of coming of age for the protagonist, was when his father, in the sauna, informed him about the biological sister or two, he had in the village, unknown to his mother. The implicit message: leave them alone ("One was rather cute" he noted with some misgivings).
Yeah, that's the Finns though. Easy to leave children behind you when you've got the whole of the Scandi peninsula and the Baltics to follow the reindeer round!!
DeleteThough... is that why parish records became a thing generally? To keep track of who in the village you can safely have kids with?
More a legal thing, probably, with inheritance etc. A gold mine for research.
DeleteNot sure genetics was widely thought about then.
It was both. Inheritance (and taxation!) were important factors, particularly because in much of pre-modern Europe, inheritance was not strictly patrilineal.
DeleteIn Denmark, for example, before Frederick V, land had be to divided equally among the children with women getting a half share, but after the land reforms, the big estates called Len (in English entailed estates) had to pass down the male line intact, which meant that it was important not just to know who your children were but also potential heirs among your cousins.
Incidentally, England had similar laws: this is what drives the plot in Jane Austen's Pride and Prejudice, for example. Mr. Bennett is relatively wealthy, but his daughters and wife are faced with poverty if he dies, because all his wealth is tied up in his property and by law that has to go to his closest male relative. In this case, since he has no sons, it's a relatively unknown male cousin.
But it was also important to prevent what were called "consanguineous marriages": this has been the case in Europe since at least the Roman republic.
Thanks, the incest taboo has existed for a long time, in many cultures, I believe..
Delete
DeleteYup. It probably predates the Romans, but they were the first people in Europe to make laws about it and write them down.
The well documented non-paternity figure is 0.5% in the last 50 years and 0.1% per generation in the preceding 1000 years (UK figures)
DeleteFor this business to be a drug discovery company would imbue it with all the integrity of Theranos. Arrogance of Silicon Valley royalty.
ReplyDeleteIt was more a target discovery company that hoped to pivot in to drugs.
DeleteIt's biggest problem was that it never actually had a clearly defined commercial goal.
DeleteRipe for identity theft
ReplyDeleteNote that the California DoJ Attorney General issued urgent advice for 23andMe customers to delete their data on Friday: https://oag.ca.gov/news/press-releases/attorney-general-bonta-urgently-issues-consumer-alert-23andme-customers
ReplyDeleteIt seems sensible to follow the instructions to avoid your data being caught up as assets for sale.
Good advice
DeleteThe data is more or less worthless on an individual level.
Deleteunless they can link it back to That Individual ?
Delete“They” - come on now. And so what? Finding out I have a likelihood of contracting dementia is hardly proof positive.
DeleteBut think of what I can advertise to you when the dementia kicks in!
DeleteI thought they had already sold the data?
DeleteSilly advice should someone buy as a going concern you would have to get tested all over again.
DeleteWojcicki has run this business into the ground with her blind ambition.
ReplyDeleteHer vignette on Bloomberg was a big, red flag—as many of them are. They should do a ‘where are they now’.